The formula to calculate Bicarb Vd for Male is:
\[ \text{Bicarb Vd} = \left(0.4 + \frac{2.6}{\text{Measured HCO3}}\right) \times \text{Lean Body Weight} \]
Where:
Bicarb Vd for Male is the volume of distribution of bicarbonate which is distributed in body tissue rather than the plasma.
Let's assume the following values:
Using the formula:
\[ \text{Bicarb Vd} = \left(0.4 + \frac{2.6}{5}\right) \times 60 \]
Evaluating:
\[ \text{Bicarb Vd} = \left(0.4 + 0.52\right) \times 60 \]
\[ \text{Bicarb Vd} = 0.92 \times 60 \]
\[ \text{Bicarb Vd} = 55.2 \]
The Bicarb Vd is 55.2 Cubic Meter per Kilogram.
| Measured HCO3 (mol/m³) | Lean Body Weight (kg) | Bicarb Vd (Cubic Meter per Kilogram) |
|---|---|---|
| 4 | 50 | 52.500000000000 |
| 4 | 55 | 57.750000000000 |
| 4 | 60 | 63.000000000000 |
| 4 | 65 | 68.250000000000 |
| 4 | 70 | 73.500000000000 |
| 5 | 50 | 46.000000000000 |
| 5 | 55 | 50.600000000000 |
| 5 | 60 | 55.200000000000 |
| 5 | 65 | 59.800000000000 |
| 5 | 70 | 64.400000000000 |
| 6 | 50 | 41.666666666667 |
| 6 | 55 | 45.833333333333 |
| 6 | 60 | 50.000000000000 |
| 6 | 65 | 54.166666666667 |
| 6 | 70 | 58.333333333333 |