Lille Score Calculator

Formula

The formula to calculate the Lille Score (LS) is:

\[ LS = 0.953 \times \log \left( \frac{\text{bilirubin day 7}}{\text{bilirubin day 0}} \right) - 0.101 \times \text{age} + 0.147 \times \text{albumin day 0} - 0.02 \times \text{prothrombin time day 0} + 2.53 \]

Where:

\( LS \) is the Lille Score
\( \text{bilirubin day 7} \) is the bilirubin level on day 7
\( \text{bilirubin day 0} \) is the bilirubin level on day 0
\( \text{age} \) is the patient's age
\( \text{albumin day 0} \) is the albumin level on day 0
\( \text{prothrombin time day 0} \) is the prothrombin time on day 0

Definition

Lille Score (LS): A clinical tool used to assess the response of patients with alcoholic hepatitis to corticosteroid treatment.
Significance: A high Lille score indicates a poor response to treatment and a higher risk of mortality, suggesting that alternative treatments may be necessary.

Example

Let's say the bilirubin level on day 7 is 1.5, the bilirubin level on day 0 is 2.0, the age is 50, the albumin level on day 0 is 3.5, and the prothrombin time on day 0 is 12. Using the formula:

\[ LS = 0.953 \times \log \left( \frac{1.5}{2.0} \right) - 0.101 \times 50 + 0.147 \times 3.5 - 0.02 \times 12 + 2.53 = 1.23 \]

So, the Lille Score (LS) is 1.23.