Liver Steatosis Index Calculator

Formula

The formula to calculate the Liver Steatosis Index (LSI) is:

\[ LSI = 8 \left( \frac{ALT}{AST} \right) + BMI + \text{(Gender)} + \text{(Diabetes Mellitus)} \]

Where:

\(LSI\) is the Liver Steatosis Index
\(ALT\) is the Alanine Aminotransferase level (U/L)
\(AST\) is the Aspartate Aminotransferase level (U/L)
\(BMI\) is the Body Mass Index (kg/m²)
Gender is represented by a binary variable (0 for male, 2 for female)
Diabetes Mellitus is represented by a binary variable (0 for absence, 2 for presence)

Liver Steatosis Definition

Liver steatosis, also known as fatty liver, is a condition characterized by the accumulation of excess fat in the liver. This can be caused by various factors such as excessive alcohol consumption, obesity, diabetes, or high cholesterol. If left untreated, it can lead to more serious liver diseases such as cirrhosis or liver cancer. It is often asymptomatic in the early stages, but can cause symptoms like fatigue, weight loss, and abdominal pain as it progresses.

Example Calculation

Let's assume the following values:

Alanine Aminotransferase (ALT) level = 40 U/L
Aspartate Aminotransferase (AST) level = 30 U/L
Body Mass Index (BMI) = 25 kg/m²
Gender = Female
Diabetes Mellitus = Yes

Using the formula to calculate the Liver Steatosis Index (LSI):

\[ LSI = 8 \left( \frac{40}{30} \right) + 25 + 2 + 2 = 8 \left( 1.33 \right) + 25 + 4 = 10.64 + 25 + 4 = 39.64 \]

The Liver Steatosis Index (LSI) is 39.64.