To calculate the MDRD score:
\[ \text{MDRD} = 186 \times \left(\frac{\text{Creatinine}}{88.4}\right)^{-1.154} \times \text{Age}^{-0.203} \times (0.742 \text{ if female}) \times (1.210 \text{ if African American}) \]
The MDRD (Modification of Diet in Renal Disease) is a formula used by healthcare professionals to estimate the glomerular filtration rate (GFR) of a patient, which is a measure of kidney function. The MDRD takes into account the patient's age, gender, race, and serum creatinine level. This formula is particularly useful in detecting early kidney disease and determining its stage in patients.
Let's assume the following values:
Using the formula:
\[ \text{MDRD} = 186 \times \left(\frac{100}{88.4}\right)^{-1.154} \times 50^{-0.203} \times 1 \times 1 \]
The MDRD Score (eGFR) is approximately 72.92 mL/min/1.73m2.
Let's assume the following values:
Using the formula:
\[ \text{MDRD} = 186 \times \left(\frac{120}{88.4}\right)^{-1.154} \times 60^{-0.203} \times 0.742 \times 1.210 \]
The MDRD Score (eGFR) is approximately 51.12 mL/min/1.73m2.