The formula to calculate the Carboplatin AUC Dose for Female is:
\[ \text{Carboplatin AUC Dose} = \text{Target AUC} \times (\text{GFR for Female} + 25) \]
Where:
Carboplatin AUC Dose for Female is used for calculating the dose based upon a patient's glomerular filtration rate and carboplatin target area under the concentration versus time curve.
Let's assume the following values:
Using the formula:
\[ \text{Carboplatin AUC Dose} = 5 \times (92 + 25) \]
Evaluating:
\[ \text{Carboplatin AUC Dose} = 5 \times 117 \]
\[ \text{Carboplatin AUC Dose} = 585 \]
The Carboplatin AUC Dose is 585 mg.
Target AUC | GFR for Female (mL/min) | Carboplatin AUC Dose (mg) |
---|---|---|
4 | 80 | 420.000000000000 |
4 | 85 | 440.000000000000 |
4 | 90 | 460.000000000000 |
4 | 95 | 480.000000000000 |
4 | 100 | 500.000000000000 |
5 | 80 | 525.000000000000 |
5 | 85 | 550.000000000000 |
5 | 90 | 575.000000000000 |
5 | 95 | 600.000000000000 |
5 | 100 | 625.000000000000 |
6 | 80 | 630.000000000000 |
6 | 85 | 660.000000000000 |
6 | 90 | 690.000000000000 |
6 | 95 | 720.000000000000 |
6 | 100 | 750.000000000000 |