The formula to calculate the Carboplatin AUC Dose for Male is:
\[ \text{Carboplatin AUC Dose for Male} = \text{Target AUC} \times (\text{GFR for Male} + 25) \]
Where:
Carboplatin AUC Dose for Male is used for calculating the dose based upon a patient's glomerular filtration rate and carboplatin target area under the concentration versus time curve.
Let's assume the following values:
Using the formula:
\[ \text{Carboplatin AUC Dose for Male} = 5 \times (95 + 25) \]
Evaluating:
\[ \text{Carboplatin AUC Dose for Male} = 5 \times 120 \]
\[ \text{Carboplatin AUC Dose for Male} = 600 \]
The Carboplatin AUC Dose for Male is 600 mg.
| Target AUC | GFR for Male (mL/min) | Carboplatin AUC Dose for Male (mg) | 
|---|---|---|
| 4 | 90 | 460.00 | 
| 4 | 92 | 468.00 | 
| 4 | 94 | 476.00 | 
| 4 | 96 | 484.00 | 
| 4 | 98 | 492.00 | 
| 4 | 100 | 500.00 | 
| 4.5 | 90 | 517.50 | 
| 4.5 | 92 | 526.50 | 
| 4.5 | 94 | 535.50 | 
| 4.5 | 96 | 544.50 | 
| 4.5 | 98 | 553.50 | 
| 4.5 | 100 | 562.50 | 
| 5 | 90 | 575.00 | 
| 5 | 92 | 585.00 | 
| 5 | 94 | 595.00 | 
| 5 | 96 | 605.00 | 
| 5 | 98 | 615.00 | 
| 5 | 100 | 625.00 | 
| 5.5 | 90 | 632.50 | 
| 5.5 | 92 | 643.50 | 
| 5.5 | 94 | 654.50 | 
| 5.5 | 96 | 665.50 | 
| 5.5 | 98 | 676.50 | 
| 5.5 | 100 | 687.50 | 
| 6 | 90 | 690.00 | 
| 6 | 92 | 702.00 | 
| 6 | 94 | 714.00 | 
| 6 | 96 | 726.00 | 
| 6 | 98 | 738.00 | 
| 6 | 100 | 750.00 |