Risk of Malignancy Index (RMI) Calculator

Formula

To calculate the Risk of Malignancy Index (RMI):

\[ RMI = U \times M \times CA125 \]

Where:

\( RMI \) is the Risk of Malignancy Index
\( U \) is the ultrasound score
\( M \) is the menopausal status (1 for premenopausal, 3 for postmenopausal)
\( CA125 \) is the serum CA125 level (U/ml)

What is the Risk of Malignancy Index (RMI)?

The Risk of Malignancy Index (RMI) is a scoring system used in gynecology to assess the risk of ovarian cancer in women presenting with an ovarian cyst or mass. It combines three diagnostic components: the ultrasound score, menopausal status, and serum CA-125 level (a blood protein that is often higher in women with ovarian cancer). The RMI is calculated by multiplying these three factors together, with a higher score indicating a higher risk of malignancy.

Example Calculation 1

Let's assume the following values:

Ultrasound Score \( U \) = 3
Menopausal Status \( M \) = 3 (postmenopausal)
Serum CA125 Level \( CA125 \) = 100 U/ml

Step 1: Multiply the ultrasound score by the menopausal status:

\[ U \times M = 3 \times 3 = 9 \]

Step 2: Multiply the result by the serum CA125 level:

\[ RMI = 9 \times 100 = 900 \]

So, the Risk of Malignancy Index (RMI) is 900.

Example Calculation 2

Let's assume the following values:

Ultrasound Score \( U \) = 2
Menopausal Status \( M \) = 1 (premenopausal)
Serum CA125 Level \( CA125 \) = 50 U/ml

Step 1: Multiply the ultrasound score by the menopausal status:

\[ U \times M = 2 \times 1 = 2 \]

Step 2: Multiply the result by the serum CA125 level:

\[ RMI = 2 \times 50 = 100 \]

So, the Risk of Malignancy Index (RMI) is 100.